| Study Links Antioxidant Resveratrol to Lower | | | | inhibition of protease enzymes. Proteases are |
| Incidence of Alzheimers | | | | used throughout an organism for various |
| Scientists from the Litwin-Zucker Research | | | | metabolic processes, including the natural process |
| Center for the Study of Alzheimer's Disease and | | | | of cells to degrade damaged proteins. By acting |
| Memory Disorders at the North Shore-Long Island | | | | as a protease inhibitor, resveratrol prevents the |
| Jewish Institute for Medical Research located in | | | | abnormal accumulation of the Amyloyd, thereby |
| New York, conducted a study to determine | | | | reducing the risk factors for Alzheimer's disease. |
| whether consumption of red wine was associated | | | | Resveratrol Supplements as a Potential Natural |
| with a lower incidence of Alzheimer's disease due | | | | Therapy |
| to its rich content of antioxidant compounds such | | | | The findings of the study demonstrate that |
| as Resveratrol. | | | | resveratrol acts as anti-amyloidogenic agent, |
| The study focused on the levels of Amyloid | | | | suggesting that this antioxidant compound has a |
| (ΑΒ) protein found in organ cells. | | | | therapeutic potential in Alzheimer's disease |
| Abnormal accumulation of this type of amyloids | | | | patients. |
| plays a crucial role in the development of | | | | The strong concentrations of polyphenols used |
| neurodegenerative diseases like Alzheimer's. The | | | | for this research study were much higher than |
| cells were treated with increased concentrations | | | | what can be obtained by drinking moderate |
| of the different polyphenols found in red wine, | | | | amounts of red wine. Nutritional supplements |
| including resveratrol, quercetin, and catechin. | | | | containing high doses of resveratrol are available in |
| How Resveratrol Inhibits Cell Degradation in | | | | the nutraceutical market, but the benefits of this |
| Alzheimer's | | | | powerful antioxidant can be easily lost when the |
| Amongst the three polyphenols, Resveratrol | | | | supplements come in the form of pills or capsules |
| proved to be the most effective. While | | | | that have to be swallowed into the digestive |
| Resveratrol does not inhibit Amyloid | | | | system. Buccal delivery resveratrol tablets and |
| (ΑΒ) production, it promotes its | | | | lozenges are absorbed through the lining tissue of |
| intracellular degradation, markedly lowering the | | | | the mouth without swallowing, and are designed |
| levels of secreted and intracellular ΑΒ | | | | to better attain the effects and dosages of |
| peptides produced from different cell lines. By this | | | | resveratrol used in studies as the compound is |
| process, amyloid plaques are prevented from | | | | more directly delivered into the blood stream. |
| forming in the brain of persons afflicted with | | | | Scientific studies have found that intraoral |
| Alzheimers disease. | | | | absorption of resveratrol supplements may |
| The mechanism through which Resveratrol | | | | produce up to 300 times greater bioavailability of |
| reduces the proliferation of | | | | resveratrol in plasma. |
| Amyloyd-ΑΒ peptides involves the | | | | |