Key Players And Innovative Start-Ups In Nutraceuticals: Emerging Strategies In Ingredients, Pharma, Food And Drinks-Aarkstore Enterprise

Pharmaceuticals, on the other hand, are bioactive				Introduction 39
compounds intended for use in the diagnosis, cure,				Market Leaders: Case studies 40
mitigation, treatment, or prevention of disease.				Case study: Nestlé 40
Pharmaceuticals are most often new chemical				Case study: Unilever 46
entities.				Case study: Groupe Danone 50
Well known nutraceuticals include essential fatty				Case study: PepsiCo 54
acids such as omega-3 oils, probiotics, prebiotics,				Case study: Coca-Cola 56
plant sterols, botanicals, superfruit extracts,				Conclusions 58
carotenoid antioxidants and soy protein				Chapter 3 Market leaders: Ingredients 62
isoflavones. Over the past few years, most of				Summary 62
these nutraceutical ingredients have made good				Introduction 63
progress in the marketplace and are now available				Companies with diverse nutraceutical portfolios 64
in a wide range of foods and drinks, as well as				Case study: DSM Nutritionals 64
supplements. Some have also been developed as				Case study: Cognis 68
pharmaceuticals.				Case study: Cargill Inc 70
The consumer environment is driving growth in				Case study: Ajinomoto 72
the nutraceuticals market. Over the past decade,				Case study: Kerry Group 74
consumers have become more concerned for				Case study: Glanbia Foods 76
their health and are increasingly inclined to				Probiotics 79
self-medicate. Healthcare providers, too, are keen				Case study: Chr. Hansen 79
to shift some of the burden of healthcare costs				Case study: Danisco 82
to individuals and recognize that functional foods				Prebiotics 85
may provide alternatives to medications. These				Case study: BENEO 85
factors are reflected in the current market for				Fats and oils 87
ingredients in the health and nutrition sector, which				Case study: Ocean Nutrition Canada 88
was estimated to be worth US$4 billion in 2009.				Agriculture 91
Key features of this report				Case study: Dow AgroSciences 92
• Identify leading companies at the forefront				Case study: Monsanto 93
of the nutraceuticals industry who will drive the				Case study: DuPont 93
market for a new generation of "value added"				Conclusions 94
health products.				Chapter 4 Market Leaders: Pharmaceutical
• Provide case studies of these leading				companies 96
companies in the finished goods (foods and				Summary 96
drinks), ingredients and other raw materials, or				Introduction 97
pharmaceutical sectors.				Market leaders: Case studies 99
• Analyze the key trends and issues				Case Study: Abbott Nutrition 99
confronting the different industry sectors at this				Case study: Bayer Consumer Care 101
time.				Case study: Pfizer 103
• Review the backgrounds, discovery				Case study: GSK Consumer Healthcare 105
strategies and business models of new and				Case study: McNeil Nutritionals 107
innovative entrants to this marketplace.				Case study: Mead Johnson Nutritionals 108
Scope of this report				Discussion 109
• Identify the companies leading the field in the				Chapter 5 Developing new ingredients: Innovative
nutraceuticals industry from across a range of				start-up companies 112
different market sectors				Summary 112
• Review their key products and the ways in				Introduction 113
which these products are being marketed to				Case study: Advana Science 115
consumers				Case study: WellGen Inc 116
• Learn more about the increased efforts of				Case study: InterMed Discovery 118
these companies to establish the health benefits				Case study: Provexis 119
of their products in clinical trials				Case study: Clasado Ltd 122
• Identify innovative companies and discover				Case study: Cambridge Theranostics Ltd 123
the potential of their various approaches for				Case Study: HerbalScience Group 125
discovery and marketing novel nutraceuticals				Business models 126
Key Market Issues				Conclusions 130
• The food market is changing: Over the past				Chapter 6 Market drivers and trends 132
decade, consumers have become more				Summary 132
concerned for their health and are increasingly				Introduction 133
inclined to self-medicate. Healthcare providers, too,				Regulatory considerations 133
are keen to shift some of the burden of				Japan 134
healthcare costs to individuals and recognize that				United States 135
functional foods may provide alternatives to				Europe 137
medications. These factors are reflected in the				Intellectual property 140
current market for ingredients in the health and				Development costs 141
nutrition sector, which was estimated to be worth				Opportunities in the nutraceuticals market 142
US$4billion in 2009.				Opportunities for medical foods 144
• Nutraceuticals and pharmaceuticals are				International emerging markets 146
related in that both are types of compound that				The science driving the future foods market 148
demonstrate bioactive properties. Nutraceuticals				Nutrigenomics and nutrigenetics 148
are substances that are extracted from foods				Epigenetics 148
and are used either to fortify other food products				Nanotechnology 149
in order to enhance their nutritional properties or				Conclusions 149
are taken as dietary supplements in the form of				Chapter 7 Appendix 152
pills, capsules of soft-gels. The clinical evidence				Primary research methodology 152
behind a nutraceutical products varies widely;				Acknowledgments 152
some have been tested with pharmaceutical rigor				Glossary 153
to demonstrate properties beneficial to health,				Index 156
while for other the evidence to support such				Bibliography 158
claims is slim.				Endnotes 163
Key findings from this report				List of Figures
• New food and drink regulations were				Figure 1.1: Different types of medical food and
introduced in Europe in 2006 and have been				their uses 22
generating uncertainty and frustration throughout				Figure 1.2: The health and nutrition sector 32
the industry. The European Food Safety Authority				Figure 1.3: Key US consumer health concerns,
is processing more than 4,000 generic health				2009 33
claims, as well as health claims for emerging and				Figure 1.4: The role of food and pharmaceuticals in
proprietary science or disease risk reduction. The				the healthcare continuum 34
regulator has rejected a large number of the				Figure 1.5: End products for nutraceutical
applications reviewed to date (September 2009)				ingredients 35
and has missed a number of deadlines, suggesting				Figure 2.1: Danone's sales figures by business line
that the overall process may take much longer				and sales region (2008) 50
than expected.				Figure 3.1: Technologies for nutraceutical product
• FDA regulations are generally regarded as				development at Kerry Group 75
less stringent than those in the EU. Nevertheless,				Figure 3.2: Defining Danisco's Bioactives and
they come under criticism for not allowing				Enabler ingredients 82
companies to use in their product labeling relevant				Figure 5.1: InterMed Discovery's active ingredient
data generated in a clinical setting that links the				pipeline 118
food with a health benefit. Some of the smaller,				Figure 5.2: A comparison of research paradigms in
innovative companies reviewed for this report are				the pharmaceutical and nutraceutical industries 127
developing their business models with this fact in				Figure 5.3: Examples of business models adopted
mind.				by innovative nutraceutical companies 128
Key questions answered				Figure 6.1: Opportunities and threats for the
• Which companies are the market leaders in				nutraceuticals industry 133
the nutraceuticals industry, as identified from a				Figure 6.2: Types of EFSA health claims 138
review of finished goods companies, raw materials				Figure 6.3: Key attributes for product success 143
manufacturers and pharmaceutical companies?				Figure 6.4: Opportunities for medical foods 145
• What are the key products of these				Figure 6.5: Growth in the number of potential
companies and how do they exemplify the future				consumers from developing and emerging
direction of the nutraceutical industry?				countries: 2008-2018 147
• How are the market leaders approaching the				List of Tables
need for research to back their products with				Table 1.1: Examples of nutraceuticals 23
health claims that are understandable by the				Table 1.2: Omega-3 and Omega-6 fatty acids and
consumer?				their dietary sources 24
				Table 1.3: Examples of common antioxidants
				present in food 30
Table of Contents :				Table 2.1: Leading food companies: revenues and
Table of Contents				product focus 39
Key Players and Innovative Start-ups in				Table 2.2: Nestlé sales by product area (CHFm),
Nutraceuticals: Emerging strategies in ingredients,				2008 40
pharma, food and drinks				Table 2.3: Nestlé's Branded Active Benefits 42
Executive summary 10				Table 2.4: Examples of brands from Nestlé
Defining nutraceuticals 10				Nutrition 43
Market leaders: food and drinks manufacturers 11				Table 2.5: Functional ingredients included in
Market leaders: ingredients 12				Danone's dairy products 51
Market leaders: pharmaceutical companies 13				Table 3.6: Market leaders: Ingredients 63
Developing new ingredients: innovative start-up				Table 3.7: Nutraceutical or personalized nutrition
companies 14				companies participated in by DSM Venturing 67
Market drivers and trends 15				Table 3.8: Examples of ingredients from Danisco
Chapter 1 Defining nutraceuticals 18				83
Summary 18				Table 4.1: Market Leaders: Pharma 98
Introduction 19				Table 4.2: Leading nutraceutical products from
Defining nutraceuticals 20				Abbott Nutrition 100
Examples of nutraceuticals 22				Table 4.3: Leading nutraceutical products from
Omega-3 oils 24				Bayer Consumer Care 102
Probiotics 25				Table 4.4: Leading nutritional products from Pfizer
Prebiotics 28				104
Plant stanols and sterols 29				Table 5.1: Innovative companies and start-ups in
Superfruits and antioxidants 30				the nutraceutical sector 114
The nutraceuticals market 31				Table 5.2: Examples of innovative companies
Report outline 34				exploring novel manufacturing methods 115
Chapter 2 Market leaders: Food and drinks				Table 5.3: Products or projects in development at
companies 38				Provexis 120
Summary 38				Table 6.

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Key Players And Innovative Start-Ups In Nutraceuticals: Emerging Strategies In Ingredients, Pharma, Food And Drinks-Aarkstore Enterprise